Decline in immune function is a hallmark of aging, leading to increased susceptibility to infections and reduced response to vaccination in the elderly population. Paradoxically this decline in immune function is associated with low grade chronic inflammation and increased incidence of diseases characterized with a marked inflammatory component...
Senior and New Scholars Awards for University of California - Irvine
Dr. Anshu Agrawal
University of California - Irvine
2006 new Scholar Award in aging
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Dr. Douglas C. Wallace
University of California - Irvine
1999 senior Scholar Award in aging
Evidence continues to accumulate that aging is associated with a decline in mitochondrial function, suggesting that mitochondrial dysfunction maybe a major factor in the pathophysiology of aging and senescence. The mitochondria provide most of the cellular energy through oxidative phosphorylation (OXPHOS), and generate most of the endogenous... |
Dr. Samuel E. Schriner
University of California - Irvine
2008 new Scholar Award in aging
The free radical theory of aging was proposed by Denham Harman more than 50 years ago, and has been perhaps the most actively studied mechanistic theory of aging. It is based on the idea that oxygen free radicals, in particular mitochondrial superoxide, are normally generated within cells, yet are toxic. Cells have defense systems against these...
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Dr. Alan G. Barbour
University of California - Irvine
2001 senior Scholar Award in gid
Several insects and ticks transmit infectious agents to humans through their saliva while they feed on the host's blood. During and after this time, these arthropods are susceptible to antibodies and other substances in the blood that are taken into the midguts of their intestinal tracts. If there is disruption of the midgut, this interferes...
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Non-Scholar Awards for University of California - Irvine
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1999 Course Scholar Award in Aging
The Ellison Medical Foundation funded a three-week summer course on the Molecular Biology of Aging at the Marine Biological Laboratory, Woods Hole, MA for the years 1999 through 2001. The course was directed by Drs. Leonard Guarente and Douglas C. Wallace. Funds cover all expenses for attending students (graduate students, post-docs, junior...
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Funded Institutions
The Ellison Medical Foundation fosters research by means of grants-in-aid on behalf of investigators to universities and laboratories within the United States. Institutions receiving awards must be tax-exempt 501(c)(3) organizations or U.S. colleges or universities.
The Ellison Medical Foundation